Amides of lysergic acid are collectively known as lysergamides, and include a number of compounds with potent agonist and/or antagonist activity at various serotonin and dopamine receptors. ...
History and possible effects of Lysergamides
Lysergamides can technically be classified as complex tryptamines, like Ibogaine. Ergoline refers to a class of compounds derived from alkaloids of a group of fungi known as ergot in the claviceps genus. These compounds typically have strong psychedelic effects. A lot of research chemicals of this family were described by Alexander Shulgin in his book TiHKAL ("Tryptamines I Have Known and Loved"), and were first described in the 1950s by Stoll and Hoffmann among several other routes reported.
The psychedelic effects of lysergamides are believed to come from its efficacy at the 5-HT2A receptor as a partial agonist. Lysergamides are known to have affinity for a much greater variety of receptors than other psychedelic research chemicals. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.
Structure of Lysergamides
Lysergamides are polycyclic amides which have both phenethylamine and tryptamine groups embedded within their structure and a carboxamide group attached to carbon number eight. Varying the substituent attached to the nitrogen atoms has produced a variety of drugs with psychedelic effects as well as prescription drugs for treating headaches and inducing labor. Hydroxylation of the aromatic ring is one method of metabolizing lysergamides in humans and produces compounds with greater affinity to dopamine receptors.
Representative compounds of this chemical class include 1cP-LSD, 1P-LSD and our brand new novel research chemical 1V-LSD (VALERIE) that are actively under research for their therapeutic and psychoactive properties. All these variations are created through the substitution of functional groups at the LSD compound's indole site or through derivation by different processes.
You can buy Lysergamides online through our shop, RareChems, in powder, blotter or pellet form for research purposes specially for the therapeutic disorders in which the serotonin and dopamine are directly related to. Through the modulation of serotonin and dopamine, lysergamides can modulate circadian rhythms or emotional states, and even help with neurological and hormonal activity of the body.
The hallucinogenic properties of lysergic acid diethylamide and other lysergamides have been investigated extensively. Although most of the recent research with lysergamides has focused on their pharmacology and structure–activity relationships, studies have also assessed potential therapeutic applications. The research chemicals of the Lysergamide family could be investigated too as mental stimulants and suppressants, and modulate disorders related to mental activity and mood regulation.
Special terms and conditions to buy Lysergamides
All our research chemicals, including Lysergamides, are strictly sold for laboratory and analytic purposes only. If you purchase our offered products from outside of the Netherlands, please check the legal status in your country before ordering since you're responsible for compliance with the laws of your jurisdiction.
If you want to be sure a research chemical of the Lysergamide family is available for your country, please read the product description. Another way would be to create an account with us and insert your shipping address in your account. That way, if the product is blocked for your country, the system won't allow you to add it to your cart.
Depending on the country of destination, you'll have the option to select the airmail shipping method and the registered airmail one, which is trackable and it's insured by us in the case of lost. Also, the payment method depends on the country of destination, where you should be able to pay using cryptocurrencies like Bitcoin, Litecoin, Ethereum and Monero between others, and by bank transfer in some cases.
Once we receive the payment, your order with Lysergamides will be set to accepted and we will send you a new email notification. If the payment is received before 16h (CET), your order will be dispatched the next day.
You can find more info inside the psychonautwiki page.
Note: Some products related to this category might be provided in pellet and/or blotter form only, and therefore not listed under this category. Please check the BLOTTER and PELLET categories as well.