DIAZEPINE

History and possible effects of Diazepines

The first such drug, chlordiazepoxide (Librium), was discovered accidentally by Leo Sternbach in 1955, and made available in 1960 by Hoffmann–La Roche, which, since 1963, has also marketed the benzodiazepine diazepam (Valium). In 1977 benzodiazepines were globally the most prescribed medications. Benzodiazepines enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABAA receptor, resulting in sedative, hypnotic (sleep-inducing), anxiolytic (anti-anxiety), anticonvulsant, and muscle relaxant properties. High doses of many shorter-acting benzodiazepines may also cause anterograde amnesia and dissociation. These properties make benzodiazepines useful in treating anxiety, insomnia, agitation, seizures, muscle spasms, alcohol withdrawal and as a premedication for medical or dental procedures. Benzodiazepines are categorized as either short, intermediary, or long-acting. Short- and intermediate-acting benzodiazepines are preferred for the treatment of insomnia; longer-acting benzodiazepines are recommended for the treatment of anxiety.

Structure of Diazepines

Benzodiazepine is a heterocyclic compound comprised of a benzene ring fused to a seven-member nitrogenous diazepine ring. Benzodiazepine research chemicals contain an additional substituted phenyl ring bonded at R5, resulting in 5-phenyl-1,4-benzodiazepines with different side groups attached to the structure to create a number of drugs with different strength, duration, and efficacy.

Benzodiazepine compounds commonly contain an aromatic electrophilic substitution such as aromatic halogenation or nitration on R7 of their rings. Benzodiazepines can be subdivided into triazolobenzodiazepines and ketone substituted benzodiazepines. Triazolobenzodiazepines contain a triazole ring bonded to the benzodiazepine structure and are distinguished by the suffix "-zolam." Ketone substituted rings contain a ketone oxygen bond at R2 of their benzodiazepine structure and are distinguished by their suffix "-azepam."

Diazepines properties

You can buy Diazepines online through our shop, RareChems, in powder, blotter or pellet form for research purposes like psychology, neurology and some other therapeutic diseases. It's due to the neurostimulation and psychoactive effects depending on the Diazepine. These research chemicals could be investigated as a treatment for panic disorders, as adjuncts to selective serotonin reuptake inhibitors for treatment of obsessive-compulsive disorder, and as adjuncts to antipsychotics for treatment of acute mania or agitation.

The research chemicals of the Diazepine family could be investigated too for numerous conditions, including anxiety, insomnia, muscle relaxation, relief from spasticity caused by central nervous system pathology, and epilepsy.

Special terms and conditions to buy Diazepines

All our research chemicals, including Diazepines, are strictly sold for laboratory and analytic purposes only. If you purchase our offered products from outside of the Netherlands, please check the legal status in your country before ordering since you're responsible for compliance with the laws of your jurisdiction.

If you want to be sure a research chemical of the Diazepine family is available for your country, please read the product description. Another way would be to create an account with us and insert your shipping address in your account. That way, if the product is blocked for your country, the system won't allow you to add it to your cart.

Depending on the country of destination, you'll have the option to select the airmail shipping method and the registered airmail one, which is trackable and it's insured by us in the case of lost. Also, the payment method depends on the country of destination, where you should be able to pay using cryptocurrencies like Bitcoin, Litecoin, Ethereum and Monero between others, and by bank transfer in some cases.

Once we receive the payment, your order with Diazepines will be set to accepted and we will send you a new email notification. If the payment is received before 16h (CET), your order will be dispatched the next day.

You can find more info in the wikipedia page.

Note: Some products related to this category might be provided in pellet and/or blotter form only, and therefore not listed under this category. Please check the BLOTTER and PELLET categories as well.