blotter1cP-LSD 150mcg Blotters (RareChems Contest Limited Edition 2020)
Arylcyclohexylamines, also known as arylcyclohexamines or arylcyclohexanamines, varyingly possess NMDA receptor antagonistic, dopamine reuptake inhibitory, and μ-opioid receptor agonistic properties. Additionally, σ receptor agonistic, nACh receptor antagonistic, and D2 receptor agonistic actions have been reported for some of these agents. Antagonism of the NMDA receptor confers anesthetic, anticonvulsant, neuroprotective, and dissociative effects; blockade of the dopamine transporter mediates stimulant and euphoriant effects as well as psychosis in high amounts; and activation of the μ-opioid receptor causes analgesic and euphoriant effects. Stimulation of the σ and D2 receptors may also contribute to hallucinogenic and psychotomimetic effects. ...
History and possible effects of Arylcyclohexylamines
Phencyclidine (PCP) is believed to be the first arylcyclohexylamine with recognized anesthetic properties, but several arylcyclohexylamines were described before PCP in the scientific literature, beginning with PCA (1-phenylcyclohexan-1-amine) the synthesis of which was first published in 1907. PCE was reported in 1953 and PCMo (4-(1-phenyl-cyclohexyl)-morpholine) in 1954, with PCMo described as a potent sedative. Arylcyclohexylamine anesthetics were intensively investigated at Parke-Davis, beginning with the 1956 synthesis of phencyclidine and later the related compound ketamine. The 1970s saw the debut of these compounds, especially PCP and its analogues, as illicitly used recreational drugs due to their dissociative hallucinogenic and euphoriant effects. Since that time, the class has been expanded by scientific research into stimulant, analgesic, and neuroprotective agents, and also by clandestine chemists in search of novel recreational drugs.
Structure of Arylcyclohexylamines
An arylcyclohexylamine is composed of a cyclohexylamine unit with an aryl moiety attachment. The aryl group is positioned geminal to the amine. In the simplest cases, the aryl moiety is typically a phenyl ring, sometimes with additional substitution. The amine is usually not primary; secondary amines such as methylamino or ethylamino, or tertiary cycloalkylamines such as piperidino and pyrrolidino, are the most commonly encountered N-substituents.
You can buy Arylcyclohexilamines online through our shop, RareChems, in powder, blotter or pellet form for research purposes like Neuro-dissociative disorders or where the perception of reality could be affected by the subject. Also, another domain of investigation could be the treatment of inflammatory diseases, specially the chronic ones, and where the central nervous system could be affected causing discomfort or even pain.
On the other hand, as substances with interaction with the NMDA receptors and dopamine, arylcyclohexylamines can be used in research of identity disorders and neurodegenerative diseases. However, despite the fact that these properties are in general terms, we encourage to study chemical by chemical, since the interaction with receptors and other neurotransmitters can be different between them.
Special terms and conditions to buy Arylcyclohexylamines
All our research chemicals, including Arylcyclohexylamines, are strictly sold for laboratory and analytic purposes only. If you purchase our offered products from outside of the Netherlands, please check the legal status in your country before ordering since you're responsible for compliance with the laws of your jurisdiction.
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You can find more info in the wikipedia page.
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